Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | BAX | Q07812 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637819 | 0.82 | NPC1 (0.45) | ESR1LTA4HLMNADRD2DRD3 | |
| SCHEMBL1045799 | 0.78 | TP53 (0.38) | ESR1LTA4HALDH1A1BCHE | |
| SCHEMBL6883552 | 0.75 | ESR1 (0.56) | ESR1ESR2NR1H2LMNADRD2 | |
| SCHEMBL11637359 | 0.71 | TDP1 (0.42) | ESR1LTA4HMAPTDRD3OPRM1 | |
| Phenol SCHEMBL5874877 | 0.70 | DRD2 (0.65) | ESR1ESR2DRD2DRD3OPRM1 | |
| Phenol SCHEMBL28134716 | 0.70 | DRD2 (0.65) | ESR1ESR2DRD2DRD3OPRM1 | |
| SCHEMBL1101358 | 0.70 | L3MBTL1 (0.41) | LTA4HMAPTLMNADRD3OPRM1 | |
| SCHEMBL1836557 | 0.70 | NR1H2 (0.55) | ESR1LTA4HNR5A1ESR2NR1H2 | |
| SCHEMBL11642255 | 0.69 | NPC1 (0.41) | ESR1LTA4HMAPTDRD3OPRM1 | |
| Phenol SCHEMBL28176923 | 0.69 | ESR1 (0.54) | ESR1NR1H2MAPTDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217353-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-16 | — | — | EP | disclosed |