Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.58 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834639 | 0.80 | IKBKB (0.61) | MAOAIKBKBKDM5AMEN1KMT2A | |
| SCHEMBL9837104 | 0.79 | IKBKB (0.63) | MAOAIKBKBKDM5AMEN1KMT2A | |
| SCHEMBL9834774 | 0.78 | TTR (0.49) | MAOAIKBKBKDM5AMEN1KMT2A | |
| SCHEMBL9836063 | 0.78 | KDM4E (0.49) | MAOAIKBKBKDM5AMEN1KMT2A | |
| SCHEMBL9835674 | 0.73 | PTGS2 (0.46) | MAOAIKBKBKDM5AMEN1KMT2A | |
| SCHEMBL9837091 | 0.73 | MEN1 (0.70) | MAOAIKBKBMEN1KMT2APTGS2 | |
| SCHEMBL9837415 | 0.73 | MEN1 (0.51) | MAOAIKBKBKDM5AMEN1KMT2A | |
| SCHEMBL5677951 | 0.72 | MAOA (0.47) | MAOAIKBKBMEN1KMT2AKDM4E | |
| SCHEMBL9834724 | 0.72 | PTGS2 (0.61) | MAOAIKBKBKDM5APTGS2KDM4E | |
| SCHEMBL25196944 | 0.71 | IKBKB (0.72) | MAOAIKBKBKDM5ARELAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0175376-A2 | Xanthone derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-03-26 | — | — | EP | disclosed |