Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 15/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836789 | 0.89 | TBXAS1 (0.67) | TBXAS1CYP26A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9834671 | 0.82 | TBXAS1 (0.80) | TBXAS1CYP26A1CYP3A4CYP17A1KMT2A | |
| SCHEMBL9835771 | 0.81 | TBXAS1 (0.50) | TBXAS1CYP17A1KMT2A | |
| SCHEMBL9837432 | 0.77 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL9871091 | 0.73 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL9835676 | 0.73 | TBXAS1 (0.76) | TBXAS1 | |
| SCHEMBL9835519 | 0.71 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL9835661 | 0.69 | TBXAS1 (0.46) | TBXAS1CYP17A1KMT2A | |
| SCHEMBL9836166 | 0.69 | TBXAS1 (1.00) | TBXAS1CYP26A1CYP3A4CYP17A1KMT2A | |
| SCHEMBL9835558 | 0.68 | TBXAS1 (0.63) | TBXAS1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |