Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 9/20 | 0.32 |
| ▸ | CA9 | Q16790 | 9/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837432 | 0.86 | TBXAS1 (0.36) | TBXAS1HPGDMAPK1KDM4ENPC1 | |
| SCHEMBL9836560 | 0.79 | DHODH (0.34) | TBXAS1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9836524 | 0.78 | TBXAS1 (0.43) | TBXAS1HPGDMAPK1KDM4ENPC1 | |
| SCHEMBL9834712 | 0.75 | PNMT (0.42) | TBXAS1HPGDMAPK1KDM4ENPC1 | |
| SCHEMBL9835661 | 0.75 | TBXAS1 (0.46) | TBXAS1KDM4ESMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL9836663 | 0.74 | KDM4E (0.36) | TBXAS1HPGDMAPK1KDM4ENPC1 | |
| SCHEMBL9836635 | 0.73 | TBXAS1 (0.53) | TBXAS1 | |
| SCHEMBL9835986 | 0.73 | TBXAS1 (0.46) | TBXAS1HPGDMAPK1KDM4ENPC1 | |
| SCHEMBL9836665 | 0.72 | KDM4E (0.42) | TBXAS1HPGDMAPK1KDM4ENPC1 | |
| SCHEMBL9834823 | 0.71 | TBXAS1 (0.40) | TBXAS1HPGDMAPK1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1023013-C | Process for preparing thianaphthene derivatives | SANKYO CO (JP) | 1993-12-08 | — | — | CN | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| CN-87102672-A | Thioindol derivatives, process for their preparation and their use | — | 1987-11-04 | — | — | CN | disclosed |