Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353342 | 0.90 | — | — | |
| SCHEMBL33883 | 0.90 | — | — | |
| SCHEMBL6563191 | 0.90 | HSD17B10 (0.65) | HSD17B10TDP1TSHRALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL29135541 | 0.87 | HSD17B10 (0.62) | HSD17B10TDP1TSHRALDH1A1CYP3A4 | |
| Mequinol SCHEMBL9799436 | 0.86 | ESR2 (0.55) | ALDH1A1CYP3A4PDK2PDK4HPGD | |
| Phloroglucinol SCHEMBL4934126 | 0.85 | HSD17B10 (0.59) | HSD17B10TDP1TSHRALDH1A1CYP3A4 | |
| Acetone SCHEMBL27351306 | 0.84 | HSD17B10 (0.52) | HSD17B10TDP1TSHRALDH1A1CYP3A4 | |
| Methoxymethane SCHEMBL16619889 | 0.83 | HSD17B10 (0.80) | HSD17B10TSHRCYP3A4CA12CA1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL9799771 | 0.81 | ESR1 (0.50) | HSD17B10TSHRALDH1A1CYP3A4ESR1 | |
| Methoxymethane SCHEMBL11131655 | 0.81 | HSD17B10 (0.54) | HSD17B10TSHRALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959388-A | Preparation of phloroglucinol or its monomethyl ether | ANDENO B.V. (NL) | 1976-05-25 | — | — | US | claimed |
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0175376-A2 | Xanthone derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-03-26 | — | — | EP | disclosed |