1-Hydroxy-3-Methoxybenzene

1-Hydroxy-3-Methoxybenzene

SCHEMBL9799771

COc1cccc(O)c1.Oc1ccc(Cl)c(O)c1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
MAPT P10636 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
HSD17B10 Q99714 2/20 0.49
NR1H4 Q96RI1 2/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
GABRA1 P14867 1/20 0.45
GABRG2 P18507 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRA3 P34903 1/20 0.45
GABRA2 P47869 1/20 0.45
GABRB2 P47870 1/20 0.45
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mequinol SCHEMBL9799436 0.84 ESR2 (0.55) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL1000565 0.83 NPC1 (0.53) ESR2MAPTMEN1KMT2AHSD17B10
1-Hydroxy-3-Methoxybenzene SCHEMBL28256 0.83
1-Hydroxy-3-Methoxybenzene SCHEMBL29421717 0.83
1-Hydroxy-3-Methoxybenzene SCHEMBL27770537 0.81 ESR1 (0.62) ESR1ESR2MAPTMEN1KMT2A
1-Hydroxy-3-Methoxybenzene SCHEMBL28322080 0.81 ESR1 (0.62) ESR1ESR2MAPTMEN1KMT2A
1-Hydroxy-3-Methoxybenzene SCHEMBL27446904 0.81 ESR1 (0.62) ESR1ESR2MAPTMEN1KMT2A
1-Hydroxy-3-Methoxybenzene SCHEMBL7390774 0.81 ESR1 (0.62) ESR1ESR2MAPTMEN1KMT2A
Resorcinol SCHEMBL6870415 0.81 ALDH1A1 (0.57) HSD17B10ALDH1A1LMNATSHRCYP3A4
1-Hydroxy-3-Methoxybenzene SCHEMBL6760019 0.81 ESR1 (0.62) ESR1ESR2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5024921-A Thermally stable light-sensitive compositions with o-quinone diazide and phenolic resin used in a method of forming a positive photoresist image OCG MICROELECTRONIC MATERIALS, INC. (US) 1991-06-18 US disclosed
US-4970287-A 4-HALORESORCINOL AND 2,6-DIMETHYLOLPHENOL MONOMERS; LIGH SENSITIVE COMPOUNDS OLIN HUNT SPECIALTY PRODUCTS INC. (US) 1990-11-13 US disclosed
US-4837121-A POSITIVE-WORKING PHOTORESISTS OLIN HUNT SPECIALTY PRODUCTS INC. (US) 1989-06-06 US disclosed