Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33883 | 1.00 | — | — | |
| SCHEMBL29353342 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29135541 | 0.97 | HSD17B10 (0.62) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Phloroglucinol SCHEMBL4934126 | 0.95 | HSD17B10 (0.59) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Resorcinol SCHEMBL6870415 | 0.90 | ALDH1A1 (0.57) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Methoxymethane SCHEMBL9836653 | 0.90 | HSD17B10 (0.54) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Phenol SCHEMBL28975672 | 0.88 | HSD17B10 (0.52) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Pentachlorophenol SCHEMBL15904847 | 0.88 | HSD17B10 (0.52) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL9666291 | 0.88 | HSD17B10 (0.52) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Pyrogallol SCHEMBL8418093 | 0.86 | HSD17B10 (0.52) | HSD17B10TSHRALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863950-B1 | HAIR DYEING COMPOSITION | NOVOZYMES AS (DK) | 2001-10-10 | — | — | EP | claimed |
| EP-1137391-B1 | METHOD FOR TREATING HAIR | NOVOZYMES AS (DK) | 2004-11-03 | — | — | EP | disclosed |
| US-6572843-B1 | Combining permanent dyeing and straightening; applying to reduced hair an oxidizing enzyme (Laccase), a mediator, and a chemical oxidizing agent that produces hydrogen peroxide | NOVOZYMES, A/S (DK) | 2003-06-03 | — | — | US | disclosed |
| EP-0963192-B1 | DIAMINOBENZOIC ACID DERIVATIVES AS DYE PRECURSORS | NOVOZYMES AS (DK) | 2003-01-08 | — | — | EP | disclosed |
| EP-1076494-B1 | RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS | NOVOZYMES AS (DK) | 2002-09-18 | — | — | EP | disclosed |
| US-20020007524-A1 | Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage | NOVOZYMES A/S (DK) | 2002-01-24 | — | — | US | disclosed |
| US-20020004958-A1 | Dyeing substrates | NOVOZYMES A/S (DK) | 2002-01-17 | — | — | US | disclosed |
| EP-0863950-B1 | HAIR DYEING COMPOSITION | NOVOZYMES AS (DK) | 2001-10-10 | — | — | EP | disclosed |
| EP-0865465-B1 | LACCASES WITH IMPROVED DYEING PROPERTIES | NOVOZYMES AS (DK) | 2001-05-30 | — | — | EP | disclosed |
| US-5948121-A | PERMANENT DYEING OF KERATINOUS FIBERS. LACCASE DERIVED FROM A STRAIN OF THE GENUS MYCELIOPHTHORA | NOVO NORDISK A/S (DK) | 1999-09-07 | — | — | US | disclosed |
| US-5899212-A | CLEAVAGE OF DISULFIDE BONDS, OXIDOREDUCTASE | NOVO NORDISK A/S (DK) | 1999-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004958-A1 | Dyeing substrates | KRT18, COL1A1, MT-ND1 | HSD17B10 67/4885TSHR 4873/4885ALDH1A1 16/4885 |
| US-20020007524-A1 | Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage | KRT18, CYB5R3, ADH7 | HSD17B10 64/4885TSHR 3797/4885ALDH1A1 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.