Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 10/20 | 0.33 |
| ▸ | CA9 | Q16790 | 10/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835738 | 0.85 | TBXAS1 (0.33) | KDM4EMAPK1TBXAS1NPC1HPGD | |
| SCHEMBL9834823 | 0.80 | TBXAS1 (0.40) | KDM4EMAPK1ALDH1A1TBXAS1NPC1 | |
| SCHEMBL9836524 | 0.78 | TBXAS1 (0.43) | KDM4EMAPK1TBXAS1NPC1HPGD | |
| SCHEMBL9834712 | 0.78 | PNMT (0.42) | KDM4EMAPK1ALDH1A1MEN1MAPT | |
| SCHEMBL9835838 | 0.77 | KDM4E (0.35) | KDM4EMAPK1ALDH1A1MEN1CYP1A2 | |
| SCHEMBL9835986 | 0.76 | TBXAS1 (0.46) | KDM4EMAPK1TBXAS1NPC1HPGD | |
| SCHEMBL9836665 | 0.75 | KDM4E (0.42) | KDM4EMAPK1ALDH1A1MAPTTBXAS1 | |
| SCHEMBL9871091 | 0.74 | TBXAS1 (0.36) | KDM4EMAPK1ALDH1A1TBXAS1NPC1 | |
| SCHEMBL9837432 | 0.73 | TBXAS1 (0.36) | KDM4EMAPK1ALDH1A1TBXAS1NPC1 | |
| SCHEMBL10777645 | 0.72 | TBXAS1 (0.39) | KDM4EMAPK1ALDH1A1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |