Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 13/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834618 | 0.83 | TBXAS1 (0.52) | TBXAS1ALDH1A1GAAKDM4EAHR | |
| SCHEMBL9835177 | 0.79 | TBXAS1 (0.53) | TBXAS1ALDH1A1GAAKDM4EL3MBTL1 | |
| SCHEMBL9836779 | 0.78 | TBXAS1 (0.76) | TBXAS1KDM4EAHRNPSR1CYP19A1 | |
| SCHEMBL9835184 | 0.72 | TBXAS1 (0.61) | TBXAS1ALDH1A1GAAKDM4EAHR | |
| SCHEMBL9834944 | 0.71 | KDM4E (0.42) | ALDH1A1GAAKDM4EL3MBTL1HPGD | |
| SCHEMBL9834927 | 0.70 | TBXAS1 (0.80) | TBXAS1ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL8068167 | 0.70 | TBXAS1 (0.64) | TBXAS1ALDH1A1KDM4E | |
| SCHEMBL9835495 | 0.70 | TBXAS1 (0.80) | TBXAS1ALDH1A1GAACYP19A1RAB9A | |
| SCHEMBL26743183 | 0.69 | KDM4E (0.49) | ALDH1A1GAAKDM4EL3MBTL1HPGD | |
| SCHEMBL9834831 | 0.69 | TBXAS1 (0.69) | TBXAS1ALDH1A1GAAL3MBTL1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |