Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835177 | 0.87 | TBXAS1 (0.53) | TBXAS1ALDH1A1ALPGALPITDP1 | |
| Imitrodast SCHEMBL166460 | 0.81 | TBXAS1 (1.00) | TBXAS1 | |
| Imitrodast SCHEMBL99497 | 0.81 | TBXAS1 (0.98) | TBXAS1 | |
| SCHEMBL9835155 | 0.80 | TBXAS1 (0.79) | TBXAS1ALDH1A1GAA | |
| Imitrodast SCHEMBL8156405 | 0.74 | TBXAS1 (0.81) | TBXAS1ALDH1A1CYP19A1 | |
| SCHEMBL9837297 | 0.72 | TBXAS1 (0.64) | TBXAS1ALDH1A1CYP19A1GAA | |
| SCHEMBL9835122 | 0.71 | TBXAS1 (0.70) | TBXAS1ALDH1A1ALPGALPITDP1 | |
| SCHEMBL9837312 | 0.69 | TBXAS1 (0.56) | TBXAS1 | |
| SCHEMBL9836683 | 0.69 | TBXAS1 (0.52) | TBXAS1ALDH1A1TDP1L3MBTL1CYP19A1 | |
| SCHEMBL9836779 | 0.69 | TBXAS1 (0.76) | TBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |