Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835184 | 0.89 | TBXAS1 (0.61) | TBXAS1KDM4EAHRNPSR1 | |
| Imitrodast SCHEMBL166460 | 0.86 | TBXAS1 (1.00) | TBXAS1 | |
| Imitrodast SCHEMBL8156405 | 0.85 | TBXAS1 (0.81) | TBXAS1KDM4ECYP19A1 | |
| Imitrodast SCHEMBL99497 | 0.85 | TBXAS1 (0.98) | TBXAS1 | |
| SCHEMBL9835177 | 0.83 | TBXAS1 (0.53) | TBXAS1KDM4EAHRNPSR1CYP19A1 | |
| SCHEMBL9835676 | 0.83 | TBXAS1 (0.76) | TBXAS1KDM4EAHRNPSR1CYP19A1 | |
| SCHEMBL9836523 | 0.81 | TBXAS1 (0.74) | TBXAS1 | |
| SCHEMBL9401600 | 0.79 | TBXAS1 (0.67) | TBXAS1KDM4ECYP19A1 | |
| SCHEMBL9835663 | 0.78 | TBXAS1 (0.43) | TBXAS1KDM4ENPC1 | |
| SCHEMBL9836683 | 0.78 | TBXAS1 (0.52) | TBXAS1KDM4EAHRNPSR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62252784-A | — | — | None | — | — | JP | disclosed |
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| JP-S62252784-A | THIANAPHTHENE DERIVATIVE AND PRODUCTION THEREOF | SANKYO CO LTD | 1987-11-04 | — | — | JP | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |