SCHEMBL9837098

SCHEMBL9837098

C=C(C)C(OC(=O)Nc1ccc(Cl)c(OC)c1)C(=O)OCC(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.56
GRM4 Q14833 2/20 0.42
HDAC6 Q9UBN7 1/20 0.42
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
MAOB P27338 3/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
MAPT P10636 2/20 0.39
RAB9A P51151 1/20 0.39
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAOA P21397 1/20 0.37
TP53 P04637 1/20 0.37
PKM P14618 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837090 0.91 SMN1; SMN2 (0.46) SMN1; SMN2GRM4HDAC6LMNAHTT
SCHEMBL9835269 0.89 GRM4 (0.47) SMN1; SMN2GRM4HDAC6LMNAHTT
SCHEMBL9835684 0.86 SMN1; SMN2 (0.43) SMN1; SMN2LMNAHTTTSHRMAPK1
SCHEMBL9837299 0.85 SMN1; SMN2 (0.42) SMN1; SMN2HDAC6LMNAHTTTSHR
SCHEMBL9834024 0.85 SMN1; SMN2 (0.42) SMN1; SMN2HDAC6LMNAHTTTSHR
SCHEMBL9836102 0.85 SMN1; SMN2 (0.42) SMN1; SMN2HDAC6LMNAHTTTSHR
SCHEMBL9837424 0.85 SMN1; SMN2 (0.42) SMN1; SMN2HDAC6LMNAHTTTSHR
SCHEMBL9836398 0.81 RORC (0.49) SMN1; SMN2GRM4HDAC6LMNAHTT
SCHEMBL9836051 0.81 RORC (0.48) SMN1; SMN2GRM4LMNAHTTMAPK1
SCHEMBL27439036 0.80 HPGD (0.39) SMN1; SMN2LMNAHTTTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same 1987-07-29 CN disclosed