SCHEMBL9835684

SCHEMBL9835684

C=C(C)C(OC(=O)Nc1ccc(Cl)c(OCCCCC)c1)C(=O)OCC(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.43
NPC1 O15118 2/20 0.41
HPGD P15428 2/20 0.41
RAB9A P51151 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
FAAH O00519 7/20 0.40
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
C5 P01031 1/20 0.38
TSHR P16473 2/20 0.38
MAPK1 P28482 1/20 0.38
EPHX2 P34913 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
EBP Q15125 1/20 0.36
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837424 0.99 SMN1; SMN2 (0.42) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL9837299 0.99 SMN1; SMN2 (0.42) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL9836102 0.99 SMN1; SMN2 (0.42) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL9834024 0.99 SMN1; SMN2 (0.42) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL9837098 0.86 SMN1; SMN2 (0.56) SMN1; SMN2HPGDRAB9ALMNAHTT
SCHEMBL9837090 0.85 SMN1; SMN2 (0.46) SMN1; SMN2HPGDRAB9ALMNAHTT
SCHEMBL9836050 0.85 L3MBTL1 (0.41) LMNAL3MBTL1TSHRTDP1KDM4E
SCHEMBL27695375 0.85 HPGD (0.39) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL27319105 0.85 HPGD (0.39) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL27439036 0.85 HPGD (0.39) SMN1; SMN2NPC1HPGDRAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same 1987-07-29 CN disclosed