SCHEMBL9837299

SCHEMBL9837299

C=C(C)C(OC(=O)Nc1ccc(Cl)c(OCCCCCC)c1)C(=O)OCC(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.42
NPC1 O15118 2/20 0.41
HPGD P15428 2/20 0.41
RAB9A P51151 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
C5 P01031 1/20 0.40
FAAH O00519 8/20 0.39
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
EBP Q15125 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
TSHR P16473 2/20 0.37
MAPK1 P28482 1/20 0.37
EPHX2 P34913 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836102 1.00 SMN1; SMN2 (0.42) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL9837424 1.00 SMN1; SMN2 (0.42) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL9834024 1.00 SMN1; SMN2 (0.42) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL9835684 0.99 SMN1; SMN2 (0.43) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL27319105 0.86 HPGD (0.39) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL27695375 0.86 HPGD (0.39) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL27439036 0.86 HPGD (0.39) SMN1; SMN2NPC1HPGDRAB9ACYP1A2
SCHEMBL9836050 0.86 L3MBTL1 (0.41) LMNAL3MBTL1EBPSIGMAR1TSHR
SCHEMBL9837098 0.85 SMN1; SMN2 (0.56) SMN1; SMN2HPGDRAB9ALMNAHTT
SCHEMBL9837090 0.84 SMN1; SMN2 (0.46) SMN1; SMN2HPGDRAB9ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed