Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 13/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835464 | 0.87 | TBXAS1 (0.53) | TBXAS1CYP11B1CYP11B2ALDH1A1GAA | |
| SCHEMBL9836741 | 0.80 | TBXAS1 (0.53) | TBXAS1ALDH1A1GAA | |
| SCHEMBL9837142 | 0.75 | TBXAS1 (1.00) | TBXAS1CYP11B1CYP11B2ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9836713 | 0.74 | TBXAS1 (0.98) | TBXAS1CYP11B1CYP11B2ALDH1A1GAA | |
| SCHEMBL9834596 | 0.73 | TBXAS1 (1.00) | TBXAS1CYP11B1CYP11B2ALDH1A1GAA | |
| SCHEMBL9835706 | 0.73 | TBXAS1 (0.72) | TBXAS1CYP11B1CYP11B2ALDH1A1GAA | |
| Imitrodast SCHEMBL166460 | 0.72 | TBXAS1 (1.00) | TBXAS1 | |
| Hydrochloric Acid SCHEMBL9836537 | 0.72 | TBXAS1 (0.98) | TBXAS1CYP11B1CYP11B2ALDH1A1GAA | |
| Imitrodast SCHEMBL99497 | 0.71 | TBXAS1 (0.98) | TBXAS1 | |
| SCHEMBL9837500 | 0.71 | TBXAS1 (0.80) | TBXAS1CYP11B1CYP11B2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |