Imitrodast

Imitrodast

SCHEMBL166460

O=C(O)C1=Cc2sc(Cn3ccnc3)cc2CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imitrodast SCHEMBL99497 0.99 TBXAS1 (0.98) TBXAS1
Imitrodast SCHEMBL8156405 0.89 TBXAS1 (0.81) TBXAS1
SCHEMBL9835155 0.88 TBXAS1 (0.79) TBXAS1
SCHEMBL9836779 0.86 TBXAS1 (0.76) TBXAS1
SCHEMBL9836523 0.85 TBXAS1 (0.74) TBXAS1
Imitrodast SCHEMBL1794449 0.84 TBXAS1 (0.71) TBXAS1
SCHEMBL9834831 0.81 TBXAS1 (0.69) TBXAS1
SCHEMBL9836890 0.81 TBXAS1 (1.00) TBXAS1
SCHEMBL9401596 0.80 TBXAS1 (0.67) TBXAS1
SCHEMBL9401600 0.80 TBXAS1 (0.67) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1962797-B2 POWDER COMPOSITIONS FOR INHALATION JAGOTEC AG (CH) 2024-05-29 EP claimed
EP-1962797-B1 POWDER COMPOSITIONS FOR INHALATION JAGOTEC AG (CH) 2020-10-28 EP claimed
US-10703826-B2 Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof CYDEX PHARMACEUTICALS, INC. (US) 2020-07-07 US claimed
EP-3354263-A1 DRY POWDER FORMULATIONS Jagotec AG (CH) 2018-08-01 EP claimed
EP-3275435-A1 DRY POWDER FORMULATIONS Jagotec AG (CH) 2018-01-31 EP claimed
EP-1689360-B1 DRY POWDER FORMULATIONS JAGOTEC AG (CH) 2017-08-23 EP claimed
US-9040483-B2 Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor BIOVASCULAR, INC. (US) 2015-05-26 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20150037425-A1 POWDER COMPOSITIONS FOR INHALATION JAGOTEC AG (CH) 2015-02-05 US claimed
CN-104224720-A DRY POWDER FORMULATIONS JAGOTEC AG 2014-12-24 CN claimed
US-20070071690-A1 Dry powder formulations JAGOTEC AG (CH) 2007-03-29 US claimed
CN-1878537-A Dry powder formulations JAGOTEC AG (CH) 2006-12-13 CN claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-1131059-B1 DRY POWDER FOR INHALATION JAGO RES AG (CH) 2003-03-05 EP claimed
EP-1283036-A1 Dry powder for inhalation JAGO RESEARCH AG (CH) 2003-02-12 EP claimed
EP-1131059-A1 DRY POWDER FOR INHALATION JAGO RESEARCH AG (CH) 2001-09-12 EP claimed
WO-2000028979-A1 DRY POWDER FOR INHALATION JAGO RESEARCH AG (CH) 2000-05-25 WO claimed
EP-0240107-B1 THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE Sankyo Company Limited (JP) 1991-08-21 EP claimed
US-4847272-A ANTICOAGULANTS SANKYO COMPANY LIMITED (JP) 1989-07-11 US claimed
EP-0240107-A1 Thianaphthene derivatives, their production and use Sankyo Company Limited (JP) 1987-10-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10703826-B2 Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof SAE1, SDC4, SPECC1L TBXAS1 2982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.