Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612645 | 0.82 | SMN1; SMN2 (0.46) | HDAC1ALDH1A1GAAHTTALOX15 | |
| SCHEMBL3280295 | 0.76 | MLKL (0.44) | GAAHTTALOX15 | |
| SCHEMBL1883961 | 0.75 | HDAC1 (0.60) | TSHRHDAC1HTTALOX15PTPN11 | |
| SCHEMBL30251598 | 0.74 | TSHR (0.64) | TSHRL3MBTL1ALDH1A1GAAPPARA | |
| SCHEMBL866718 | 0.74 | TSHR (0.64) | TSHRL3MBTL1ALDH1A1GAAPPARA | |
| SCHEMBL477483 | 0.74 | HPGD (0.49) | GAAALOX15CA12CA1CA2 | |
| SCHEMBL19029299 | 0.73 | HDAC1 (0.50) | HDAC1ALDH1A1GAAHTTALOX15 | |
| SCHEMBL15697489 | 0.73 | HDAC1 (0.61) | HDAC1ALDH1A1HTTALOX15PTPN11 | |
| SCHEMBL3340488 | 0.73 | TSHR (0.58) | TSHRL3MBTL1ALDH1A1GAAPPARA | |
| SCHEMBL6299396 | 0.73 | HDAC1 (0.50) | HDAC1ALDH1A1GAAHTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| CN-87102672-A | Thioindol derivatives, process for their preparation and their use | — | 1987-11-04 | — | — | CN | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |