Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 17/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174942 | 0.96 | IKBKB (0.38) | IKBKB | |
| SCHEMBL9167969 | 0.91 | IKBKB (0.43) | IKBKBALDH1A1LMNARIPK1CHUK | |
| SCHEMBL9837095 | 0.90 | RIPK1 (0.39) | IKBKBALDH1A1RIPK1 | |
| SCHEMBL9168566 | 0.89 | IKBKB (0.41) | IKBKBALDH1A1LMNARIPK1CHUK | |
| SCHEMBL8132620 | 0.89 | IKBKB (0.40) | IKBKBALDH1A1LMNARIPK1 | |
| SCHEMBL9171221 | 0.88 | RIPK1 (0.43) | IKBKBALDH1A1LMNARIPK1CHUK | |
| SCHEMBL9836709 | 0.88 | IKBKB (0.41) | IKBKBALDH1A1LMNARIPK1CHUK | |
| SCHEMBL9173723 | 0.88 | IKBKB (0.44) | IKBKBALDH1A1LMNARIPK1CHUK | |
| SCHEMBL9173066 | 0.88 | ALDH1A1 (0.41) | IKBKBALDH1A1LMNARIPK1 | |
| SCHEMBL9172086 | 0.88 | IKBKB (0.41) | IKBKBALDH1A1LMNARIPK1CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422051-A1 | CONDENSED PYRAZOLE 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-04-17 | — | — | EP | disclosed |
| WO-1989012630-A1 | CONDENSED PYRAZOLE 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-12-28 | — | — | WO | disclosed |
| EP-0347773-A1 | Condensed Pyrazole 3-oxo-propanenitrile derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1989-12-27 | — | — | EP | disclosed |