Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | AOC2 | O75106 | 5/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837005 | 0.81 | MAOA (0.41) | MAOAMAOBNISCHHTR1AHTR1D | |
| SCHEMBL9835181 | 0.81 | MAOA (0.41) | MAOAMAOBHTR2ANISCHHTR1A | |
| Hydrochloric Acid SCHEMBL9835668 | 0.79 | MAOA (0.40) | MAOAMAOBNISCHHTR1AHTR1D | |
| SCHEMBL10706601 | 0.77 | MAOA (0.38) | MAOAMAOBNISCHHTR1AHTR1D | |
| SCHEMBL9836246 | 0.69 | MTNR1A (0.40) | HTR1AHTR1D | |
| SCHEMBL1917308 | 0.67 | MAOB (0.48) | MAOAMAOBHTR2ANISCHHTR1A | |
| SCHEMBL1648508 | 0.67 | MAOA (0.59) | MAOAMAOB | |
| SCHEMBL31151882 | 0.67 | MAOA (0.59) | MAOAMAOB | |
| SCHEMBL28671200 | 0.67 | MAOA (0.39) | MAOAMAOBHTR2ANISCHAOC2 | |
| SCHEMBL6997509 | 0.65 | HTR2A (0.66) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129879-B1 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4547496-A | Antiulcer [1] benzepino[3,4-b]pyridine and compositions | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-10-15 | — | — | US | disclosed |
| EP-0129879-A2 | A [1] benzepino(3,4-b)pyridine derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |