Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL8579080 | 0.94 | LMNA (0.45) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL9638880 | 0.85 | ELANE (0.43) | CYP3A4NPC1RAB9AKDM4EPOLB | |
| SCHEMBL1788142 | 0.81 | CYP3A4 (0.57) | LMNACYP3A4ACHEKMT2AMEN1 | |
| Phosphonic Acid SCHEMBL8582001 | 0.81 | ELANE (0.39) | CYP3A4NPC1RAB9AKDM4EPOLB | |
| Phosphonic Acid SCHEMBL8583461 | 0.79 | CES2 (0.40) | LMNAKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL338192 | 0.77 | CYP3A4 (0.65) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL11435725 | 0.76 | CYP3A4 (0.62) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL869141 | 0.76 | CYP3A4 (0.58) | LMNACYP3A4ACHEALDH1A1KDM4E | |
| SCHEMBL249305 | 0.74 | LMNA (0.76) | LMNACYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL17028900 | 0.74 | LMNA (0.76) | LMNACYP3A4ACHEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003479-A1 | SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | TROPIX, INC. (US) | 1991-03-21 | — | — | WO | disclosed |