Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.79 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.79 |
| ▸ | EDNRA | P25101 | 1/20 | 0.79 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.79 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007797 | 0.92 | LMNA (0.67) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8044673 | 0.92 | LMNA (0.79) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11153426 | 0.91 | LMNA (0.82) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10028900 | 0.90 | LMNA (0.81) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10108591 | 0.89 | LMNA (0.75) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL12665451 | 0.89 | LMNA (0.75) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL29384458 | 0.88 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11080390 | 0.88 | LMNA (0.78) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL33963 | 0.88 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL2635855 | 0.88 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824405-B | Acrylic ketone derivative of N-methyl enoxacin and preparation method and application thereof | 河南大学 | 2023-06-02 | — | — | CN | disclosed |
| US-8231897-B2 | Hydrostatic delivery system for controlled delivery of agent | MACGREGOR ALEXANDER (CA) | 2012-07-31 | — | — | US | disclosed |
| US-20080317847-A1 | HYDROSTATIC DELIVERY SYSTEM FOR CONTROLLED DELIVERY OF AGENT | MACGREGOR ALEXANDER | 2008-12-25 | — | — | US | disclosed |
| US-7381424-B2 | Hydrostatic delivery system for controlled delivery of agent | MACGREGOR ALEXANDER | 2008-06-03 | — | — | US | disclosed |
| EP-1347748-A2 | HYDROSTATIC DELIVERY SYSTEM FOR CONTROLLED DELIVERY OF AGENT | MacGregor, Alexander (CA) | 2003-10-01 | — | — | EP | disclosed |
| US-20020155067-A1 | Hydrostatic delivery system for controlled delivery of agent | MACGREGOR ALEXANDER (CA) | 2002-10-24 | — | — | US | disclosed |
| WO-2002045695-A2 | HYDROSTATIC DELIVERY SYSTEM FOR CONTROLLED DELIVERY OF AGENT | MACGREGOR ALEXANDER (CA) | 2002-06-13 | — | — | WO | disclosed |
| EP-0169105-B1 | CONTROLLED POROSITY OSMOTIC PUMP | MERCK & CO. INC. (US) | 1991-08-07 | — | — | EP | disclosed |
| US-4968507-A | SUSTAINED RELEASE OF DRUG | MERCK & CO., INC. (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0208617-B1 | CONTROLLED DRUG DEVICE AND PROCESS FOR CATALYSING THE EROSION OF AN ACID LABILE POLYMER | MERCK & CO. INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4851228-A | Multiparticulate controlled porosity osmotic | MERCK & CO., INC. (US) | 1989-07-25 | — | — | US | disclosed |
| US-4780319-A | DRUG DELIVERY USING POLYORTHOESTERS COATINGS | MERCK & CO., INC. (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0208617-A1 | Controlled drug device and process for catalysing the erosion of an acid labile polymer | MERCK & CO. INC. (US) | 1987-01-14 | — | — | EP | disclosed |
| EP-0169105-A2 | Controlled porosity osmotic pump | MERCK & CO. INC. (US) | 1986-01-22 | — | — | EP | disclosed |
| US-4496566-A | ANTIBACTERIAL AGENT | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1985-01-29 | — | — | US | disclosed |
| US-4359578-A | Naphthyridine derivatives and salts thereof useful as antibacterial agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1982-11-16 | — | — | US | disclosed |
| US-4352803-A | BACTERICIDES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0009425-A1 | Novel naphtyridine derivatives and pharmaceutical compositions containing them | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1980-04-02 | — | — | EP | disclosed |