Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 6/20 | 0.49 |
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837257 | 0.90 | ALDH1A1 (0.46) | IKBKBKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL9836660 | 0.82 | ALDH1A1 (0.55) | CYP1A2CYP2C9KDM4EMEN1ALDH1A1 | |
| SCHEMBL9836198 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1GAA | |
| SCHEMBL9834409 | 0.77 | KDM4E (0.41) | KDM4EKMT2A | |
| SCHEMBL10737753 | 0.76 | NPC1 (0.41) | KDM4EALDH1A1GAAHPGDKMT2A | |
| SCHEMBL6050600 | 0.71 | KDM4E (0.43) | KDM4EMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL10341064 | 0.70 | KDM4E (0.71) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL30542063 | 0.70 | KDM4E (0.71) | KDM4EMEN1ALDH1A1KMT2A | |
| Water SCHEMBL9837052 | 0.70 | KDM4E (0.42) | KDM4EMEN1ALDH1A1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL29812500 | 0.69 | KDM4E (0.41) | IKBKBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269295-B1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1991-06-26 | — | — | EP | disclosed |
| US-4877793-A | CARDIOVASCULAR DISORDERS | THE BOOTS COMPANY, PLC (GB) | 1989-10-31 | — | — | US | disclosed |
| EP-0269295-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1988-06-01 | — | — | EP | disclosed |