Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 3/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838630 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9837418 | 0.87 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9375324 | 0.87 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL8699900 | 0.82 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Hydrochloric Acid SCHEMBL8566204 | 0.81 | ALDH1A1 (0.72) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9749429 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9837590 | 0.80 | LMNA (0.61) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9838598 | 0.80 | LMNA (0.61) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL10572143 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10574238 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | claimed |
| US-4571396-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-02-18 | — | — | US | claimed |
| EP-0159174-A2 | Substituted naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-10-23 | — | — | EP | claimed |
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |
| US-4571396-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0159174-A2 | Substituted naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-10-23 | — | — | EP | disclosed |