Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.71 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.62 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | XDH | P47989 | 4/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | AGER | Q15109 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247012 | 0.92 | LMNA (0.82) | LMNAAKR1C3AKR1C2AKR1C1GAA | |
| SCHEMBL11883939 | 0.90 | LMNA (0.66) | LMNAAKR1C3AKR1C2AKR1C1GAA | |
| SCHEMBL20322862 | 0.84 | LMNA (1.00) | LMNAAKR1C3AKR1C2AKR1C1GAA | |
| SCHEMBL13479654 | 0.83 | AKR1C3 (1.00) | LMNAAKR1C3AKR1C2AKR1C1GAA | |
| SCHEMBL9835886 | 0.83 | AKR1C3 (0.57) | LMNAAKR1C3AKR1C2AKR1C1GAA | |
| SCHEMBL31193434 | 0.82 | TTR (0.62) | LMNAAKR1C3AKR1C2AKR1C1GAA | |
| SCHEMBL9836869 | 0.82 | LMNA (0.59) | LMNAAKR1C3AKR1C2AKR1C1GAA | |
| SCHEMBL6519242 | 0.81 | MAOA (0.70) | KMT2AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL9834762 | 0.81 | LMNA (0.57) | LMNAAKR1C3AKR1C2AKR1C1GAA | |
| SCHEMBL30748196 | 0.81 | XDH (0.67) | ACSL1ACSL6NPC1MAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |