Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.58 |
| ▸ | CTSV | O60911 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | MAX | P61244 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | THPO | P40225 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837317 | 0.85 | ANO1 (0.57) | KMT2AMAPTMEN1CTSVCTSL | |
| SCHEMBL4205393 | 0.84 | CRHBP (0.70) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL9834480 | 0.84 | CRHBP (0.70) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL4214475 | 0.84 | CRHBP (0.70) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL9838079 | 0.81 | MAPT (0.58) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL17434401 | 0.80 | MAPT (0.70) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL31521409 | 0.80 | MEN1 (0.52) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| Hydrochloric Acid SCHEMBL6852305 | 0.79 | MAPT (0.55) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL3032927 | 0.78 | CTSV (0.71) | KMT2AMAPTMEN1PLA2G1BATG4B | |
| SCHEMBL5265055 | 0.76 | MAPT (0.64) | KMT2AMAPTMEN1PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994493-A | Treatment of cerebral edema | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN (DE) | 1991-02-19 | — | — | US | disclosed |