Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.33 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355924 | 0.79 | SHMT2 (0.45) | SHMT2SMN1; SMN2ALDH1A1MAPTNPSR1 | |
| SCHEMBL10365982 | 0.77 | TDP1 (0.44) | LMNAALDH1A1MAPTTDP1HTT | |
| SCHEMBL10992140 | 0.76 | CFTR (0.37) | LMNASMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL9838652 | 0.76 | SHMT2 (0.39) | SHMT2LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10365714 | 0.74 | MAPK1 (0.38) | LMNAALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL10366017 | 0.74 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL30945117 | 0.74 | SHMT2 (0.41) | SHMT2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9838712 | 0.74 | SHMT2 (0.41) | SHMT2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9837609 | 0.73 | SHMT2 (0.40) | SHMT2ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL9839357 | 0.71 | SHMT2 (0.39) | SHMT2ALDH1A1MAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230874-B1 | BENZOTHIAZOLYLAZOLIDINES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0218972-B1 | BENZOTHIAZOLONES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-07 | — | — | EP | disclosed |
| US-4898948-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-06 | — | — | US | disclosed |
| US-4888428-A | HERBICIDE INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-12-19 | — | — | US | disclosed |
| US-4828605-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-09 | — | — | US | disclosed |
| US-4786310-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-22 | — | — | US | disclosed |
| US-4720297-A | Benzothiazolones, and their production and use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0230874-A1 | Benzothiazolylazolidines, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-08-05 | — | — | EP | disclosed |
| EP-0218972-A1 | Benzothiazolones, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-22 | — | — | EP | disclosed |