Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837540 | 0.76 | SHMT2 (0.42) | CFTRALDH1A1GFERTDP1ATM | |
| SCHEMBL10913762 | 0.75 | MAPT (0.47) | ALDH1A1TDP1ATMHIF1AMAPT | |
| SCHEMBL3862000 | 0.75 | HDAC1 (0.42) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL11003744 | 0.74 | SHMT2 (0.39) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL31717475 | 0.73 | GLS (0.38) | CFTRALDH1A1GFERTDP1ATM | |
| SCHEMBL4303327 | 0.70 | CYP3A4 (0.36) | CFTRALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL1490111 | 0.68 | BRPF1 (0.53) | ALDH1A1GFERTDP1MAPTMEN1 | |
| SCHEMBL3857344 | 0.67 | CYP3A4 (0.36) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL9838652 | 0.67 | SHMT2 (0.39) | CFTRALDH1A1GFERTDP1MAPT | |
| SCHEMBL8442790 | 0.67 | CA12 (0.47) | ALDH1A1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61194074-A | — | — | None | — | — | JP | disclosed |
| JP-S61194074-A | 7-AMINO-1-ALKYL-6-FLUOROQUINOLIN-2(1H)-ONE AND ITS PREPARATION | SUMITOMO CHEM CO LTD | 1986-08-28 | — | — | JP | disclosed |