Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837630 | 0.81 | MEN1 (0.47) | GAAMAPTALDH1A1MAP1LC3BTSHR | |
| SCHEMBL9837769 | 0.75 | MAPT (0.46) | GAAPOLBMAPTALDH1A1MAP1LC3B | |
| SCHEMBL9834910 | 0.74 | KMT2A (0.43) | GAAMAPTALDH1A1MAP1LC3BTSHR | |
| SCHEMBL9835656 | 0.69 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL21795277 | 0.68 | POLB (0.50) | GAAPOLBMAPTALDH1A1MAP1LC3B | |
| SCHEMBL2656962 | 0.66 | MAPT (0.55) | GAAPOLBMAPTALDH1A1TSHR | |
| SCHEMBL9836885 | 0.66 | GRM2 (0.42) | ALDH1A1MAP1LC3BKMT2ALMNAHPGD | |
| SCHEMBL22111733 | 0.65 | POLB (0.54) | GAAPOLBMAPTALDH1A1MAP1LC3B | |
| SCHEMBL1781059 | 0.65 | MAP1LC3B (0.59) | GAAPOLBMAPTALDH1A1MAP1LC3B | |
| SCHEMBL1781122 | 0.65 | MAPT (0.57) | GAAPOLBMAPTALDH1A1MAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261674-B1 | A CYCLOHEXANEDIONE DERIVATIVE AND A PROCESS FOR PRODUCING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4863925-A | SUBSTITUTED | NIHON NOHYAKU CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0261674-A1 | A cyclohexanedione derivative and a process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 1988-03-30 | — | — | EP | disclosed |