Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837630 | 0.80 | MEN1 (0.47) | MAPTKMT2AALDH1A1SMN1; SMN2MAP1LC3B | |
| SCHEMBL9837030 | 0.79 | MAPT (0.38) | MAPTTDP1POLBNPSR1KMT2A | |
| SCHEMBL9837566 | 0.75 | GAA (0.42) | MAPTPOLBNPSR1KMT2AALDH1A1 | |
| SCHEMBL9845996 | 0.74 | MAPT (0.43) | MAPTTDP1POLBNPSR1KMT2A | |
| SCHEMBL9834910 | 0.73 | KMT2A (0.43) | MAPTKMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9845971 | 0.69 | TDP1 (0.38) | MAPTTDP1POLBNPSR1KMT2A | |
| SCHEMBL9835656 | 0.68 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL9836885 | 0.65 | GRM2 (0.42) | KMT2AALDH1A1MAP1LC3BHPGDPKM | |
| SCHEMBL1177395 | 0.64 | POLB (1.00) | MAPTTDP1POLBNPSR1KMT2A | |
| SCHEMBL21218882 | 0.63 | CHRM5 (0.54) | MAPTTDP1POLBNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261674-B1 | A CYCLOHEXANEDIONE DERIVATIVE AND A PROCESS FOR PRODUCING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1991-06-12 | — | — | EP | claimed |
| US-4863925-A | SUBSTITUTED | NIHON NOHYAKU CO., LTD. (JP) | 1989-09-05 | — | — | US | claimed |
| EP-0261674-A1 | A cyclohexanedione derivative and a process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 1988-03-30 | — | — | EP | claimed |