SCHEMBL9837591

SCHEMBL9837591

O=C1C=CC(=O)N1c1c(Cl)cc(O)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.43
NPSR1 Q6W5P4 4/20 0.43
HSP90AA1 P07900 4/20 0.43
MAPK1 P28482 3/20 0.43
PKM P14618 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 3/20 0.42
HSD17B10 Q99714 3/20 0.42
CYP3A4 P08684 2/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
CCR6 P51684 2/20 0.38
RAB9A P51151 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465067 0.82 MGLL (0.47) MGLLNPSR1HSP90AA1MAPK1PKM
SCHEMBL9839190 0.74 MGLL (0.43) MGLLNPSR1HSP90AA1MAPK1PKM
SCHEMBL9837786 0.74 MGLL (0.43) MGLLNPSR1HSP90AA1MAPK1PKM
SCHEMBL9837527 0.74 MGLL (0.55) MGLLNPSR1HSP90AA1MAPK1PKM
SCHEMBL3868551 0.73 MGLL (0.59) MGLLHSP90AA1PKMALDH1A1HTT
SCHEMBL3874354 0.71 MGLL (0.46) MGLLNPSR1HSP90AA1MAPK1PKM
SCHEMBL8090084 0.71 MGLL (0.48) MGLLNPSR1HSP90AA1MAPK1PKM
SCHEMBL5077491 0.70 MGLL (0.60) MGLLNPSR1HSP90AA1MAPK1PKM
SCHEMBL22863431 0.69 MGLL (0.46) MGLLNPSR1HSP90AA1MAPK1PKM
SCHEMBL28883464 0.68 MGLL (0.48) MGLLNPSR1HSP90AA1PKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075453-A Process for producing aryloxy-substituted phosphazene derivatives NIPPON SODA CO., LTD. (JP) 1991-12-24 US disclosed
US-4855389-A Process for producing phosphonitrile oligomers containing maleimidophenoxy group SHIN NISSO KAKO CO., LTD. (JP) 1989-08-08 US disclosed