Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 2/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30047213 | 0.89 | L3MBTL1 (0.47) | KDM4EL3MBTL1KDM6BKDM5CKDM4C | |
| SCHEMBL23857227 | 0.89 | L3MBTL1 (0.47) | KDM4EL3MBTL1KDM6BKDM5CKDM4C | |
| SCHEMBL30049082 | 0.83 | KDM4E (0.50) | KDM4EL3MBTL1KDM6BKDM5CKDM4C | |
| SCHEMBL9684174 | 0.83 | KDM4E (0.50) | KDM4EL3MBTL1KDM6BKDM5CKDM4C | |
| SCHEMBL28582520 | 0.82 | KDM4E (0.48) | KDM4EL3MBTL1KDM6BKDM5CKDM4C | |
| SCHEMBL28956330 | 0.81 | KDM4E (0.46) | KDM4EL3MBTL1KDM6BKDM5CKDM4C | |
| SCHEMBL28330383 | 0.81 | CA12 (0.50) | KDM4EL3MBTL1KDM6BKDM5CKDM4C | |
| SCHEMBL6578250 | 0.80 | KDM4E (0.43) | KDM4EL3MBTL1KDM6BKDM5CKDM4C | |
| Cyclopropane SCHEMBL11660772 | 0.79 | KDM4E (0.46) | KDM4EL3MBTL1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9509719 | 0.77 | LMNA (0.48) | L3MBTL1MAPK1ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980303-A | Novel compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-115298176-A | Compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-109053559-A | The preparation method of 5- methoxyl methyl -2,3- pyridinedicarboxylic acid dimethyl ester | 江苏省农用激素工程技术研究中心有限公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-0161221-B1 | PROCESS FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES AND OF 1-AMINO-1,4-DIHYDROPYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| US-4748244-A | HERBICIDE INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0161221-A2 | Process for the preparation of pyridine-2,3-dicarboxylic-acid derivatives and of 1-amino-1,4-dihydropyridine-2,3-dicarboxylic-acid derivatives | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |