Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MITF | O75030 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31304908 | 0.85 | CYP2C19 (0.46) | LMNAHSD17B10SMN1; SMN2MITFMAPT | |
| SCHEMBL20995945 | 0.83 | KDM4E (0.51) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL20995910 | 0.81 | MMP8 (0.48) | LMNASMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL20995947 | 0.81 | KMT2A (0.50) | LMNASMN1; SMN2MAPTRAB9AALDH1A1 | |
| Benzoin SCHEMBL1151761 | 0.80 | LMNA (0.58) | LMNAHSD17B10SMN1; SMN2MAPTALDH1A1 | |
| Benzoin SCHEMBL158692 | 0.79 | LMNA (0.68) | LMNAHSD17B10SMN1; SMN2MITFMAPT | |
| SCHEMBL20995937 | 0.79 | KDM4E (0.48) | LMNAHSD17B10SMN1; SMN2RAB9ATP53 | |
| SCHEMBL6203195 | 0.78 | LMNA (0.60) | LMNAHSD17B10SMN1; SMN2MITFMAPT | |
| SCHEMBL50454 | 0.78 | LMNA (0.80) | LMNAHSD17B10SMN1; SMN2MITFRAB9A | |
| SCHEMBL20995895 | 0.78 | NPC1 (0.51) | LMNASMN1; SMN2RAB9ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462150-A1 | NOVEL ARYLOXY ALKYL AMINES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM. | LAEVOSAN GMBH & CO KG (AT) | 1991-12-27 | — | — | EP | disclosed |
| WO-1990010628-A1 | NOVEL ARYLOXY ALKYL AMINES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | LAEVOSAN-GESELLSCHAFT MBH (AT) | 1990-09-20 | — | — | WO | disclosed |