Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837262 | 0.99 | CYP19A1 (0.49) | CYP19A1CHRM3SMN1; SMN2NPC1HTT | |
| SCHEMBL9838936 | 0.93 | CYP19A1 (0.41) | CYP19A1CHRM3NPC1RAB9A | |
| SCHEMBL9837621 | 0.84 | CYP19A1 (0.52) | CYP19A1CHRM3SMN1; SMN2NPC1HTT | |
| SCHEMBL9839584 | 0.83 | CYP19A1 (0.51) | CYP19A1CHRM3SMN1; SMN2NPC1HTT | |
| SCHEMBL9837903 | 0.82 | CYP19A1 (0.45) | CYP19A1CHRM3RAB9AGPR35CHRM2 | |
| SCHEMBL685797 | 0.76 | CYP19A1 (0.50) | CYP19A1CHRM3SMN1; SMN2NPC1HTT | |
| SCHEMBL686208 | 0.76 | CYP19A1 (0.50) | CYP19A1CHRM3SMN1; SMN2NPC1HTT | |
| SCHEMBL686006 | 0.76 | CYP19A1 (0.50) | CYP19A1CHRM3SMN1; SMN2NPC1HTT | |
| SCHEMBL9837560 | 0.74 | NFE2L2 (0.40) | SMN1; SMN2NPC1RAB9AHSD11B1 | |
| SCHEMBL9837558 | 0.74 | RAB9A (0.51) | SMN1; SMN2NPC1HTTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276122-B1 | CYCLOALKYL-SUBSTITUTED 4-AMINOPHENYL HALO DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-08-07 | — | — | EP | claimed |
| EP-0276122-A2 | Cycloalkyl-substituted 4-aminophenyl halo derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-07-27 | — | — | EP | claimed |
| EP-0276122-B1 | CYCLOALKYL-SUBSTITUTED 4-AMINOPHENYL HALO DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-08-07 | — | — | EP | disclosed |
| US-4847295-A | ANTITUMOR AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-07-11 | — | — | US | disclosed |
| EP-0276122-A2 | Cycloalkyl-substituted 4-aminophenyl halo derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-07-27 | — | — | EP | disclosed |