Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | GCK | P35557 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511343 | 1.00 | P4HTM (0.58) | P4HTMKDM4EMAPK1GCKESR1 | |
| SCHEMBL13881346 | 0.87 | GLA (0.46) | P4HTMKDM4EMAPK1GCKESR1 | |
| SCHEMBL12074871 | 0.81 | PAM (0.50) | P4HTMKDM4EMAPK1GCKESR1 | |
| SCHEMBL10140600 | 0.79 | P4HTM (0.33) | P4HTMKDM4EMAPK1ESR1ESR2 | |
| SCHEMBL5508613 | 0.77 | KDM4E (0.53) | P4HTMKDM4EMAPK1GCKESR1 | |
| SCHEMBL19116260 | 0.77 | GRM5 (0.49) | KDM4EMAPK1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1124260 | 0.77 | P4HTM (0.64) | P4HTMKDM4EMAPK1GCKESR1 | |
| SCHEMBL1124258 | 0.77 | P4HTM (0.64) | P4HTMKDM4EMAPK1GCKESR1 | |
| SCHEMBL8731557 | 0.77 | P4HTM (0.68) | P4HTMKDM4EMAPK1ESR1HCAR2 | |
| SCHEMBL6853074 | 0.77 | P4HTM (0.68) | P4HTMKDM4EMAPK1ESR1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210782-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |
| US-4778796-A | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0210782-A2 | Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-02-04 | — | — | EP | disclosed |