SCHEMBL6853074

SCHEMBL6853074

O=C(O)C=Cc1ccc(-c2ccc(C=CC(=O)O)cn2)nc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 2/20 0.68
KDM4E B2RXH2 5/20 0.57
ALDH1A1 P00352 3/20 0.57
HPGD P15428 3/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
MITF O75030 1/20 0.57
KLF5 Q13887 1/20 0.57
RAB9A P51151 2/20 0.54
NPC1 O15118 1/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
HCAR2 Q8TDS4 3/20 0.53
CA12 O43570 2/20 0.53
AKR1B10 O60218 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA3 P07451 2/20 0.53
AKR1B1 P15121 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731557 1.00 P4HTM (0.68) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL29789035 1.00 P4HTM (0.68) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL5293348 0.88 ALDH1A1 (0.62) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL5293356 0.88 ALDH1A1 (0.62) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL6853005 0.84 CA12 (0.57) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL11660063 0.84 P4HTM (0.68) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL11660064 0.84 P4HTM (0.68) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL3611594 0.84 KDM4E (0.61) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL3611598 0.84 KDM4E (0.61) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL9836730 0.82 P4HTM (0.66) P4HTMKDM4EALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119114162-B Heterogeneous metal photocatalyst and preparation method and application thereof 中山大学 2025-03-14 CN claimed
CN-119114162-A Heterogeneous metal photocatalyst and preparation method and application thereof 中山大学 2024-12-13 CN claimed
US-10647733-B2 Metal-organic frameworks containing nitrogen-donor ligands for efficient catalytic organic transformations THE UNIVERSITY OF CHICAGO (US) 2020-05-12 US claimed
CN-119114162-B Heterogeneous metal photocatalyst and preparation method and application thereof 中山大学 2025-03-14 CN disclosed
CN-119114162-A Heterogeneous metal photocatalyst and preparation method and application thereof 中山大学 2024-12-13 CN disclosed
US-10647733-B2 Metal-organic frameworks containing nitrogen-donor ligands for efficient catalytic organic transformations THE UNIVERSITY OF CHICAGO (US) 2020-05-12 US disclosed
US-20170182486-A1 METAL-ORGANIC FRAMEWORKS CONTAINING NITROGEN-DONOR LIGANDS FOR EFFICIENT CATALYTIC ORGANIC TRANSFORMATIONS THE UNIVERSITY OF CHICAGO (US) 2017-06-29 US disclosed
EP-0799827-B1 ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KYORIN SEIYAKU KK (JP) 2004-05-12 EP disclosed
US-5786486-A ANTIMICROBIAL, ANTITUMOR AGENTS KYORIN PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed
EP-0799827-A1 ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KYORIN PHARMACEUTICAL CO., LTD. (JP) 1997-10-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647733-B2 Metal-organic frameworks containing nitrogen-donor ligands for efficient catalytic organic transformations NCLN, MDH1, NNMT P4HTM 4822/4885KDM4E 4407/4885ALDH1A1 1706/4885
US-20170182486-A1 METAL-ORGANIC FRAMEWORKS CONTAINING NITROGEN-DONOR LIGANDS FOR EFFICIENT CATALYTIC ORGANIC TRANSFORMATIONS NCLN, MDH1, NNMT P4HTM 4822/4885KDM4E 4407/4885ALDH1A1 1706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.