Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990899 | 0.87 | KDM4E (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL29530212 | 0.84 | TGFBR1 (0.55) | KDM4ETSHRFNTAFNTBL3MBTL1 | |
| SCHEMBL34462053 | 0.83 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL29936413 | 0.81 | FOLH1 (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL29416686 | 0.81 | TSHR (0.45) | KDM4EMAPTTSHRL3MBTL1GNPAT | |
| SCHEMBL29638170 | 0.81 | ALDH1A1 (0.55) | MAPTTSHRFOLH1MMEALDH1A1 | |
| SCHEMBL2350303 | 0.79 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4321775 | 0.79 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2350309 | 0.79 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL23758996 | 0.79 | ECE1 (0.47) | KDM4ETSHRFOLH1L3MBTL1GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304778-B1 | PROCESS FOR THE PRODUCTION OF N-ACYLATED MERCAPTO-ALPHA-AMINO ACIDS | Degussa Aktiengesellschaft (DE) | 1991-10-23 | — | — | EP | disclosed |
| US-4918223-A | Method of preparing N-acylated mercapto-alpha-amino acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1990-04-17 | — | — | US | disclosed |
| EP-0304778-A1 | Process for the production of N-acylated mercapto-alpha-amino acids | Degussa Aktiengesellschaft (DE) | 1989-03-01 | — | — | EP | disclosed |