Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038246 | 0.86 | KDM4E (0.46) | GAAALDH1A1HSD17B10KDM4EGLA | |
| SCHEMBL9319322 | 0.84 | ALDH1A1 (0.40) | GAAALDH1A1KMT2AAPP | |
| SCHEMBL9067391 | 0.83 | VCAM1 (0.46) | GAAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL30209 | 0.80 | GAA (0.57) | GAAALDH1A1KMT2AHTTLMNA | |
| SCHEMBL25306694 | 0.79 | DGKA (0.47) | GAAALDH1A1KMT2A | |
| SCHEMBL29140996 | 0.79 | DGKA (0.47) | GAAALDH1A1KMT2A | |
| SCHEMBL29140974 | 0.79 | DGKA (0.47) | GAAALDH1A1KMT2A | |
| SCHEMBL29140958 | 0.79 | DGKA (0.47) | GAAALDH1A1KMT2A | |
| SCHEMBL29140984 | 0.79 | DGKA (0.47) | GAAALDH1A1KMT2A | |
| SCHEMBL29923229 | 0.79 | GAA (0.56) | GAAALDH1A1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034412-A | Antiinflammatory agents, skin disorders, antidiabetic agents or antiatherosclerosis agents | MERRELL DOW PHARMACUETICALS INC. (US) | 1991-07-23 | — | — | US | claimed |