Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325032 | 0.93 | TNKS2 (0.36) | CA2CYP4F2CYP4A11TNKS2 | |
| SCHEMBL9484014 | 0.85 | TDP1 (0.33) | CA2 | |
| SCHEMBL7305069 | 0.84 | PTGS2 (0.44) | PTGS2ACHE | |
| SCHEMBL9324995 | 0.77 | TNKS2 (0.33) | CYP4F2CYP4A11TNKS2 | |
| SCHEMBL9327493 | 0.77 | FAAH (0.41) | PTGS2 | |
| SCHEMBL9324994 | 0.76 | TRPV1 (0.33) | — | |
| SCHEMBL9327542 | 0.76 | DAGLA (0.34) | — | |
| SCHEMBL9838268 | 0.70 | CYP1A2 (0.47) | — | |
| SCHEMBL9714107 | 0.70 | PTGS2 (0.42) | PTGS2ACHE | |
| SCHEMBL10431555 | 0.69 | TNNC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059611-A | Treating psoriasis and modifying calcium homeostatis | ALLERGAN, INC. (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0369812-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |