Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983845 | 0.86 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL256016 | 0.84 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL20732767 | 0.82 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL11219791 | 0.82 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL1470264 | 0.82 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL18529844 | 0.81 | — | — | |
| SCHEMBL12132583 | 0.79 | — | — | |
| SCHEMBL712301 | 0.78 | EPHX1 (0.32) | — | |
| SCHEMBL28041651 | 0.78 | — | — | |
| SCHEMBL10743427 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388105-B2 | Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals | EASTMAN CHEMICAL COMPANY (US) | 2016-07-12 | — | — | US | claimed |
| US-8969598-B2 | Production of cyclic acetals or ketals using liquid-phase acid catalysts | EASTMAN CHEMICAL COMPANY (US) | 2015-03-03 | — | — | US | claimed |
| US-8829206-B2 | Production of cyclic acetals or ketals using solid acid catalysts | EASTMAN CHEMICAL COMPANY (US) | 2014-09-09 | — | — | US | claimed |
| WO-2012177417-A1 | PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | claimed |
| WO-2012177469-A1 | PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | claimed |
| WO-2012177485-A1 | PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | claimed |
| US-20120330033-A1 | PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | US | claimed |
| US-20120330032-A1 | PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | US | claimed |
| US-20120330069-A1 | PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | US | claimed |
| US-9440944-B2 | Production of cyclic acetals or ketals using solid acid catalysts | EASTMAN CHEMICAL COMPANY (US) | 2016-09-13 | — | — | US | disclosed |
| US-9394271-B2 | Production of cyclic acetals or ketals using liquid-phase acid catalysts | EASTMAN CHEMICAL COMPANY (US) | 2016-07-19 | — | — | US | disclosed |
| US-9388105-B2 | Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals | EASTMAN CHEMICAL COMPANY (US) | 2016-07-12 | — | — | US | disclosed |
| US-9382179-B2 | Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals | EASTMAN CHEMICAL COMPANY (US) | 2016-07-05 | — | — | US | disclosed |
| US-9315485-B2 | Production of cyclic acetals by reactive distillation | EASTMAN CHEMICAL COMPANY (US) | 2016-04-19 | — | — | US | disclosed |
| WO-2012177417-A1 | PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012177591-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| EP-0199210-B1 | CONVERSION OF 1,3-DIOXANES INTO 4-OXA-ALDEHYDES | BASF Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-4709097-A | CATALYTIC ISOMERIZATION WITH ACIDIC ZEOLITE | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | disclosed |
| EP-0199210-A2 | Conversion of 1,3-dioxanes into 4-oxa-aldehydes | BASF Aktiengesellschaft (DE) | 1986-10-29 | — | — | EP | disclosed |
| EP-0133881-A1 | Aliphatic monoethers of 2,2-dimethylpropane-1,3-diol with C3 to C20 alkoxy groups, with the exception of 3-isopropoxy-2,2-dimethylpropane-1-ol and 3-tert.butoxy-2,2-dimethylpropane-1-ol, process for their production and their use as plasticizer alcohols | HÜLS AKTIENGESELLSCHAFT (DE) | 1985-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330069-A1 | PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS | CCNE2, CCNH, HRH2 | ALDH1A1 2751/4885 |
| US-20120330032-A1 | PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS | PKLR, AKR1C4, AKR1C2 | ALDH1A1 295/4885 |
| US-20120330033-A1 | PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS | PKLR, KHK, PHYKPL | ALDH1A1 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.