Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | HPGD | P15428 | 1/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23377537 | 1.00 | MAPT (0.79) | MAPTALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL9838141 | 1.00 | MAPT (0.79) | MAPTALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL8614831 | 0.98 | ALDH1A1 (0.81) | MAPTALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL8049689 | 0.96 | MAPT (0.85) | MAPTALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL1304422 | 0.96 | MAPT (0.85) | MAPTALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL8049692 | 0.96 | MAPT (0.85) | MAPTALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL1304425 | 0.96 | MAPT (0.85) | MAPTALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL14391815 | 0.91 | ESR1 (0.73) | MAPTALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL13070554 | 0.90 | KDM4E (0.74) | MAPTALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL11311833 | 0.89 | MAPT (0.73) | MAPTALDH1A1KDM4EHPGDCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |