Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837950 | 0.93 | LMNA (0.45) | NPC1MAOAMAOBLMNACRBN | |
| SCHEMBL9344620 | 0.92 | CRBN (0.40) | NPC1MAOAMAOBLMNACRBN | |
| SCHEMBL9346012 | 0.92 | CRBN (0.39) | NPC1MAOAMAOBLMNACRBN | |
| SCHEMBL9346429 | 0.91 | LMNA (0.40) | NPC1MAOAMAOBLMNACRBN | |
| SCHEMBL9348876 | 0.91 | LMNA (0.40) | NPC1MAOAMAOBLMNACRBN | |
| SCHEMBL9346067 | 0.90 | LMNA (0.39) | NPC1MAOAMAOBLMNACRBN | |
| SCHEMBL9345716 | 0.90 | LMNA (0.39) | NPC1MAOAMAOBLMNACRBN | |
| SCHEMBL9344573 | 0.90 | LMNA (0.39) | NPC1MAOAMAOBLMNACRBN | |
| SCHEMBL9345732 | 0.90 | LMNA (0.39) | NPC1MAOAMAOBLMNACRBN | |
| SCHEMBL10349590 | 0.89 | NQO1 (0.44) | NPC1MAOAMAOBLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030383-A | With low temperature dependence of threshold voltage | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0258349-B1 | ELECTRO-OPTICAL DISPLAY ELEMENT | MERCK PATENT GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| US-4751017-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-06-14 | — | — | US | disclosed |
| EP-0258349-A1 | ELECTRO-OPTICAL DISPLAY ELEMENT. | MERCK PATENT GMBH (DE) | 1988-03-09 | — | — | EP | disclosed |
| US-4715984-A | DIELECTRICS FOR ELECTROOPTICAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-12-29 | — | — | US | disclosed |
| WO-1987005318-A1 | ELECTRO-OPTICAL DISPLAY ELEMENT | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-09-11 | — | — | WO | disclosed |
| EP-0220254-A1 | BENZONITRILES. | MERCK PATENT GMBH (DE) | 1987-05-06 | — | — | EP | disclosed |
| EP-0205503-A1 | LIQUID CRYSTALLINE PHASE. | MERCK PATENT GMBH (DE) | 1986-12-30 | — | — | EP | disclosed |
| WO-1986006372-A1 | BENZONITRILE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-11-06 | — | — | WO | disclosed |
| WO-1986003769-A1 | LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-07-03 | — | — | WO | disclosed |