Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839580 | 0.85 | MAOB (0.51) | MAOBTSHRALDH1A1MAPTLMNA | |
| SCHEMBL9838198 | 0.81 | BAZ2B (0.54) | MAOBTSHRALDH1A1MAPTLMNA | |
| SCHEMBL9838252 | 0.79 | MAOB (0.47) | MAOBTSHRALDH1A1MAPTLMNA | |
| SCHEMBL9839489 | 0.77 | MAOB (0.45) | MAOBTSHRALDH1A1MAPTLMNA | |
| SCHEMBL9840246 | 0.76 | KDM4E (0.46) | MAOBTSHRALDH1A1MAPTLMNA | |
| SCHEMBL364335 | 0.75 | TSHR (0.53) | TSHRALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL10524528 | 0.75 | KMT2A (0.42) | MAOBALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL12326552 | 0.75 | MAOB (0.56) | MAOBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7222675 | 0.75 | TSHR (0.53) | TSHRALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL31278130 | 0.73 | MAOB (0.47) | MAOBTSHRALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011944-A | Substituted α-pyrones | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |