Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839580 | 0.83 | MAOB (0.51) | MAOBALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL31171420 | 0.79 | TSHR (0.60) | ALDH1A1MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL31171418 | 0.79 | TSHR (0.60) | ALDH1A1MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL9838239 | 0.79 | MAOB (0.48) | MAOBALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL9838198 | 0.79 | BAZ2B (0.54) | MAOBALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL10522496 | 0.77 | KDM4E (0.42) | ALDH1A1MAPTLMNAKDM4EKMT2A | |
| SCHEMBL9839489 | 0.76 | MAOB (0.45) | MAOBALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL9840246 | 0.75 | KDM4E (0.46) | MAOBALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL3997791 | 0.74 | TSHR (0.58) | ALDH1A1MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL1964219 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2025480-A | — | — | None | — | — | JP | disclosed |
| US-5011944-A | Substituted α-pyrones | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| JP-H0225480-A | SUBSTITUTED ALPHA-PYRONES AND NAPHTHOQUINONES | CIBA GEIGY AG | 1990-01-26 | — | — | JP | disclosed |