Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839580 | 0.80 | MAOB (0.51) | KDM4EMAPTMAOBALDH1A1LMNA | |
| SCHEMBL10521778 | 0.78 | KDM4E (0.40) | KDM4EMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9838239 | 0.76 | MAOB (0.48) | KDM4EMAPTMAOBALDH1A1LMNA | |
| SCHEMBL9838198 | 0.76 | BAZ2B (0.54) | KDM4EMAPTMAOBALDH1A1LMNA | |
| SCHEMBL9838252 | 0.75 | MAOB (0.47) | KDM4EMAPTMAOBALDH1A1LMNA | |
| SCHEMBL28537883 | 0.74 | CA12 (0.62) | KDM4ENOD2MAPTSMN1; SMN2MAOB | |
| SCHEMBL9839489 | 0.72 | MAOB (0.45) | KDM4EMAPTMAOBALDH1A1LMNA | |
| SCHEMBL9307300 | 0.72 | LMNA (0.49) | KDM4ENOD2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1791133 | 0.71 | TSHR (0.65) | KDM4EALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL9590339 | 0.71 | KMT2A (0.46) | KDM4ENOD2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011944-A | Substituted α-pyrones | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |