Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839580 | 0.81 | MAOB (0.51) | MAOBMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10522892 | 0.77 | KMT2A (0.40) | MAPTALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL9838198 | 0.77 | BAZ2B (0.54) | MAOBMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9838239 | 0.77 | MAOB (0.48) | MAOBMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9838252 | 0.76 | MAOB (0.47) | MAOBMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9840246 | 0.72 | KDM4E (0.46) | MAOBMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL14687178 | 0.72 | CA1 (0.46) | MAPTALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL3472808 | 0.72 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL3338994 | 0.71 | MAOB (0.46) | MAOBMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2023231 | 0.70 | TSHR (0.67) | ALDH1A1LMNAL3MBTL1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011944-A | Substituted α-pyrones | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |