SCHEMBL9838249

SCHEMBL9838249

CCC(=O)O[Si](CC(=O)O)(CC(=O)O)CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.41
ALDH1A1 P00352 1/20 0.33
NAAA Q02083 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836680 0.82 ALDH1A1 (0.46) FFAR3ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL1759546 0.77 ALDH1A1 (0.38) FFAR3ALDH1A1NAAA
SCHEMBL430933 0.71 ALDH1A1 (0.41) FFAR3ALDH1A1NAAA
SCHEMBL512768 0.70 FFAR3 (0.38) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL431579 0.69 ALDH1A1 (0.39) FFAR3ALDH1A1NAAA
SCHEMBL27135126 0.69
SCHEMBL1291088 0.69
SCHEMBL7885704 0.69 ALDH1A1 (0.39) FFAR3ALDH1A1NAAA
SCHEMBL527825 0.68 FFAR3 (0.36) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL7892094 0.67 ALDH1A1 (0.38) FFAR3ALDH1A1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5061301-A Sulfonating polysulfone membrane followed by grafting with polysiloxanes and crosslinking KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1991-10-29 US claimed