Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841253 | 0.82 | KMT2A (1.00) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| Tegafur SCHEMBL7698456 | 0.82 | LMNA (1.00) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL8784500 | 0.82 | LMNA (0.69) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| Tegafur SCHEMBL4553 | 0.82 | LMNA (1.00) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| Tegafur SCHEMBL8537231 | 0.82 | LMNA (1.00) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| Tegafur SCHEMBL4552 | 0.82 | LMNA (1.00) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL19203480 | 0.82 | LMNA (0.69) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL9839754 | 0.82 | LMNA (0.69) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| Tegafur SCHEMBL22320166 | 0.81 | LMNA (0.97) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| Tegafur SCHEMBL4155129 | 0.81 | LMNA (0.97) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075446-A | Synthesis of tetrahydro-2-furylated pyrimidine derivatives | KOREA ADVANCED INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 1991-12-24 | — | — | US | disclosed |