Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | PYGM | P11217 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19203480 | 0.82 | LMNA (0.69) | KMT2AALDH1A1POLBSMN1; SMN2LMNA | |
| Tegafur SCHEMBL8537231 | 0.82 | LMNA (1.00) | KMT2AALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL8784500 | 0.82 | LMNA (0.69) | KMT2AALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL9839754 | 0.82 | LMNA (0.69) | KMT2AALDH1A1POLBSMN1; SMN2LMNA | |
| Tegafur SCHEMBL4552 | 0.82 | LMNA (1.00) | KMT2AALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL9838290 | 0.82 | ALDH1A1 (0.69) | KMT2AALDH1A1POLBSMN1; SMN2LMNA | |
| Tegafur SCHEMBL7698456 | 0.82 | LMNA (1.00) | KMT2AALDH1A1POLBSMN1; SMN2LMNA | |
| Tegafur SCHEMBL4553 | 0.82 | LMNA (1.00) | KMT2AALDH1A1POLBSMN1; SMN2LMNA | |
| Tegafur SCHEMBL22320166 | 0.81 | LMNA (0.97) | KMT2AALDH1A1POLBSMN1; SMN2LMNA | |
| Tegafur SCHEMBL4155129 | 0.81 | LMNA (0.97) | KMT2AALDH1A1POLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075446-A | Synthesis of tetrahydro-2-furylated pyrimidine derivatives | KOREA ADVANCED INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 1991-12-24 | — | — | US | disclosed |