Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | INMT | O95050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentylenetetrazol SCHEMBL22674 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MEN1MAPTBLMKMT2A | |
| Pentylenetetrazol SCHEMBL6407957 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MEN1MAPTBLMKMT2A | |
| SCHEMBL3182039 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MEN1MAPTBLMKMT2A | |
| Pentylenetetrazol SCHEMBL10408117 | 0.98 | ALDH1A1 (0.96) | ALDH1A1MEN1MAPTBLMKMT2A | |
| Pentylenetetrazol SCHEMBL15057132 | 0.98 | ALDH1A1 (0.96) | ALDH1A1MEN1MAPTBLMKMT2A | |
| Pentylenetetrazol SCHEMBL10873243 | 0.98 | ALDH1A1 (0.96) | ALDH1A1MEN1MAPTBLMKMT2A | |
| SCHEMBL2211329 | 0.98 | — | — | |
| SCHEMBL2212322 | 0.91 | — | — | |
| Pentylenetetrazol SCHEMBL2260235 | 0.87 | ALDH1A1 (0.76) | ALDH1A1MEN1MAPTBLMKMT2A | |
| Biphenyl SCHEMBL7633644 | 0.86 | ALDH1A1 (0.73) | ALDH1A1MEN1MAPTBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008452-A | Antidepressants, sedatives and anticonvulsants | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-04-16 | — | — | US | disclosed |
| US-4235931-A | ANTIDEPRESSANTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1980-11-25 | — | — | US | disclosed |
| US-4192818-A | ANTIDEPRESSANTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1980-03-11 | — | — | US | disclosed |
| US-3937841-A | AMINO-OXIME COMPOUNDS | U.S. PHILIPS CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |