Purine

Purine

SCHEMBL9838579

Nc1nc(Cc2ccccc2)nc2nc[nH]c12.c1ncc2[nH]cnc2n1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.51
PDE4B Q07343 1/20 0.51
PDE4C Q08493 1/20 0.51
PDE4D Q08499 1/20 0.51
CYP1A2 P05177 4/20 0.41
CYP2D6 P10635 4/20 0.41
LMNA P02545 4/20 0.41
CDK1 P06493 3/20 0.41
CDK2 P24941 3/20 0.41
CYP3A4 P08684 3/20 0.41
CYP2C9 P11712 3/20 0.41
CYP2C19 P33261 3/20 0.41
PIN1 Q13526 2/20 0.41
CCNB1 P14635 2/20 0.41
CCNA2 P20248 2/20 0.41
CCNA1 P78396 2/20 0.41
TSHR P16473 2/20 0.41
MGMT P16455 1/20 0.41
NFKB1 P19838 1/20 0.41
BLM P54132 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL104931 0.87 PDE4A (0.64) PDE4APDE4BPDE4CPDE4DCYP1A2
SCHEMBL29557469 0.87 PDE4A (0.64) PDE4APDE4BPDE4CPDE4DCYP1A2
Adenine SCHEMBL7891002 0.84 PI4KA (0.56) PDE4APDE4BPDE4CPDE4DCYP1A2
Phosphoric Acid SCHEMBL27565804 0.80 PDE4A (0.56) PDE4APDE4BPDE4CPDE4DCYP1A2
SCHEMBL28460506 0.78 PDE4A (0.48) PDE4APDE4BPDE4CPDE4DCYP1A2
2,6-Diaminopurine SCHEMBL28306361 0.78 PDPK1 (0.68) LMNACDK1CDK2PIN1CCNB1
6-Benzylaminopurine SCHEMBL9474231 0.77 PDE4A (0.73) PDE4APDE4BPDE4CPDE4DCYP1A2
Purine SCHEMBL9215924 0.76 LOXL2 (0.42) CYP1A2CYP2D6LMNACDK1CDK2
Purine SCHEMBL8019859 0.75 PDPK1 (0.47) LMNACDK2ALDH1A1PDPK1GDA
SCHEMBL29241588 0.74 PDE4A (0.50) PDE4APDE4BPDE4CPDE4DCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230193152-A1 METHODS AND FORMULATIONS FOR ENHANCING HIGH VALUE LIPIDS DEPARTMENT OF BIOTECHNOLOGY (IN) 2023-06-22 US claimed
EP-4198136-A2 METHODS AND FORMULATIONS FOR ENHANCING HIGH VALUE LIPIDS Indian Oil Corporation Limited (IN) 2023-06-21 EP claimed
US-20230193152-A1 METHODS AND FORMULATIONS FOR ENHANCING HIGH VALUE LIPIDS DEPARTMENT OF BIOTECHNOLOGY (IN) 2023-06-22 US disclosed
EP-4198136-A2 METHODS AND FORMULATIONS FOR ENHANCING HIGH VALUE LIPIDS Indian Oil Corporation Limited (IN) 2023-06-21 EP disclosed
WO-1991003157-A1 MONOCOTYLEDON CROP PLANTS RESISTANT TO CYCLOHEXANEDIONE AND ARYLOXY(AMINO)-PHENOXYPROPIONATE HERBICIDES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1991-03-21 WO disclosed